Benfotiamine Side Effects

Can you suffer adverse side effects when you take benfotiamine? The truth is, not really. This is backed by decades of science and research, but there are a few instances you should be aware of when taking this manufactured form of thiamine (vitamin B1), that may cause problems for certain individuals.

The health benefits of benfotiamine are such that almost everyone who is thiamine deficient, could, or should take it to avert ill health, if they are already not suffering from perhaps neurological conditions or even malnutrition!

Thiamine deficiency can even lead to metabolic coma.

Who Can Benfotiamine Really Help?

If you, or you know someone who suffers with loss of cognitive brain health, muscle soreness, or poor digestion, benfotiamine can help. And it could mean they are deficient in thiamine. Diabetics are generally deficient in thiamine, so benfotiamine can also help people suffering with diabetes, or even to help prevent the disease.

It is in lipid form, which means that it metabolizes significantly more rapid in the body, releasing generous levels of thiamine pyrophosphate (the active form of thiamine), compared to thiamine hydrochloride.

Benfotiamine is Safe When Taken Appropriate Doses

Medical literature indicates that taken in appropriate amounts benfotiamine is very safe. It has no reported interactions with food, other vitamins or prescription drugs, according to Dr. Michael Brownlee, a benfotiamine researcher at the Albert Einstein College of Medicine in New York.

Benfotiamine has been licenced for use in Germany for over a decade without any major side effect being reported according to his report. Under the supervision of a healthcare provider, prescription thiamine shots are also FDA approved.

The European Food and Safety Authority reports that no adverse side effect have been reported for benfotiamine based on human clinical studies for dosage of 40 to 400 mg per day, used for three to twelve weeks.

Who Should Avoid Taking Benfotiamine?

To date there is only one group of individuals who need to exercise caution when using benfotiamine, and these are people with solid tumour cancers. Cancer cells use thiamine to make a group of enzymes called transketolases, which use the sugar in cells as fuel without any oxygen.

This allows the cancer cells to go undetected by the human immune system while they deprive healthy neighbouring cells of nutrients. In other words, thiamine can help the spread of cancer. But, benfotiamine (or any other form of thiamine) does not cause any cancer, to be clear.


Benfotiamine Dosage

Benfotiamine is a manufactured supplement of vitamin B1 (thiamine), which has five times more bioavailable than regular thiamine. The closest form of thiamine, which is similar to benfotiamine is found in genus Allium plants like onions, garlic and leeks.

The configuration of benfotiamine allows it to transverse cell membranes readily, making its antioxidant abilities more usable for the body. Latest research indicates that benfotiamine is valuable in averting a number of oxidative-stress related ailments.

Realistically speaking, the body can only use around ten milligrams of vitamin B1 in thiamine form, in a day. Benfotiamine however, can be taken safely at much higher dosage as it is fat-soluble, not water soluble like thiamine. Most people take 600mg daily, two 150 mg capsules in the morning and two in the evening.

However some people get better results by increasing the dosage as high as 1200mg. In a study to determine the effect of benfotiamine and formation of Advanced Glycation End Products, human participants were given 600mg a day to get a 40% in AGE formation.

People simply have to work out what is best for them, higher or lower dosages, and by being prudent and monitoring their own reactions to the supplement, they can determine the dose which works best for them. Benfotiamine has no side effects at all reasonable daily dosages.

The best way to approach the dose question is to start with the typical recommended amount. The first signs of the supplement working appear two to three weeks after you begin using it, at which point the dose can be adjusted according to needs.

Important: Individuals with thiamine sensitivity need to proceed with caution, if at all. And should consult a medical professional before taking benfotiamine.

Never the less, symptoms of over dosing might include weakness, nausea, sweating, restlessness, feeling of warmth and breathing problems. The skin may also exhibit a bluish colouration. If any of these symptoms are experienced, it is best to discontinue at once.